Advances in drying technology of traditional Chinese medicine extracts: spray drying technology
2021-05-22 19:59:37
Spray drying technology has a history of more than 100 years. China's research and development of spray drying technology has a history of more than 30 years, the technology has been widely used in dairy, detergent, food and many other fields. At present, the application of spray drying technology in the Chinese medicine pharmaceutical industry has been relatively extensive. In recent years, spray drying technology has been combined with a variety of technologies such as fluidization, micro-encapsulation and coating, and its application in the field of traditional Chinese medicine has been expanding and playing an increasingly important role.
During the spray drying process of the traditional Chinese medicine extract, the Chinese medicine extract is dispersed into a mist droplet by an atomizer, and heat exchange is performed under the action of the drying medium to rapidly evaporate the solvent in the mist droplet to obtain a powdery or granular product.
Spray drying is suitable for drying heat-sensitive traditional Chinese medicine extracts. It has fast drying speed, good product quality and high purity. The process of concentration, filtration and pulverization can be omitted, and the granular product of 30~500p, m can be obtained, which is time-consuming and short, high in production efficiency, and good in product fluidity and fast-dissolving. For the Chinese medicine pharmaceutical industry, the application of spray drying technology has its unique role, which greatly simplifies the process of extracting Chinese medicine extract into semi-finished or finished products, thereby shortening the production cycle and improving production efficiency and product quality.
For traditional Chinese medicine extracts, the problem of spray-dried Zui is that it is easy to absorb moisture from sticky walls and dry products, and it is difficult to handle high-concentration, high-viscosity Chinese medicine extracts. In response to this problem, a new generation of one-step granulation Chinese medicine drying tower has been used for low-temperature drying, which can avoid the hot-melt sticky wall of the low-melting material, and can effectively shoot down the adhered dry powder in a boiling state. Research by Qu Cunhai et al. showed that the softening point of traditional Chinese medicine extract is lower than the air inlet temperature of spray drying, which is the main cause of sticking wall. By adding excipients to improve the softening point of the extract, the sticking phenomenon can be eliminated. The CS series Chinese medicine spray dryer produced by Zhejiang Erle Drying Equipment Co., Ltd. changed the sticking, moisture absorption and agglomeration phenomenon encountered by the traditional spray dryer, and did not add any auxiliary materials during the spraying process. Another drawback of spray drying is that the heat sensitive material has oxidation problems during spray drying and needs to be given sufficient attention. In addition, the spray drying equipment is large, the structure requirements are high, the energy consumption is high, the cleaning is inconvenient, and the application in the drying of the traditional Chinese medicine extract is still limited.
During the spray drying process of the traditional Chinese medicine extract, the Chinese medicine extract is dispersed into a mist droplet by an atomizer, and heat exchange is performed under the action of the drying medium to rapidly evaporate the solvent in the mist droplet to obtain a powdery or granular product.
Spray drying is suitable for drying heat-sensitive traditional Chinese medicine extracts. It has fast drying speed, good product quality and high purity. The process of concentration, filtration and pulverization can be omitted, and the granular product of 30~500p, m can be obtained, which is time-consuming and short, high in production efficiency, and good in product fluidity and fast-dissolving. For the Chinese medicine pharmaceutical industry, the application of spray drying technology has its unique role, which greatly simplifies the process of extracting Chinese medicine extract into semi-finished or finished products, thereby shortening the production cycle and improving production efficiency and product quality.
For traditional Chinese medicine extracts, the problem of spray-dried Zui is that it is easy to absorb moisture from sticky walls and dry products, and it is difficult to handle high-concentration, high-viscosity Chinese medicine extracts. In response to this problem, a new generation of one-step granulation Chinese medicine drying tower has been used for low-temperature drying, which can avoid the hot-melt sticky wall of the low-melting material, and can effectively shoot down the adhered dry powder in a boiling state. Research by Qu Cunhai et al. showed that the softening point of traditional Chinese medicine extract is lower than the air inlet temperature of spray drying, which is the main cause of sticking wall. By adding excipients to improve the softening point of the extract, the sticking phenomenon can be eliminated. The CS series Chinese medicine spray dryer produced by Zhejiang Erle Drying Equipment Co., Ltd. changed the sticking, moisture absorption and agglomeration phenomenon encountered by the traditional spray dryer, and did not add any auxiliary materials during the spraying process. Another drawback of spray drying is that the heat sensitive material has oxidation problems during spray drying and needs to be given sufficient attention. In addition, the spray drying equipment is large, the structure requirements are high, the energy consumption is high, the cleaning is inconvenient, and the application in the drying of the traditional Chinese medicine extract is still limited.
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