Bioengineering Marriage Electronic Technology - A New Era of Personalized Medicine is Coming

Experts in the academic field believe that it is time for bioengineering researchers and embedded system design engineers to begin developing devices for the new era of personalized medicine .

At the Embedded Systems Conference (ESC) in the United States, Luke P. Lee, a professor of bioengineering at the University of California, Berkeley, said that various nano-parts under development will be activated and available. Handheld devices that turn Health Care services into a system that combines innovative bioengineering components with existing computer and consumer electronics technologies.

Luke Lee, Professor of Bioengineering, University of California, Berkeley

"I predict -- or hope -- that we have moved to the final stage of basic biotechnology research and will implement new, preventive and predictive applications that combine IT, biotechnology and nanotechnology." Lee is actually He started his career in the academic field ten years ago. Before that, he worked for electronics companies such as TRW. His imaginary future medical equipment can detect personal physiological information on a weekly basis and guide people based on very sensitive biomarkers. Take an appropriate lifestyle.

“For example, this type of device can remind you that if you diet in this way, you may have a 50% chance of getting cancer.” Lee also detailed several research projects over the past decade, and these results have been Bringing new horizons to molecular-scale living cell measurement technology.

Lee said: "If these nanometer sensors are integrated with a disposable microfluidic chip, all that is needed is an optical or electronic detection subsystem, such as the iPhone. The built-in CMOS camera of the portable device. "By borrowing the naming idea of ​​the popular iPhone, he nicknamed the device that combines the mobile phone with the molecular diagnostic system.

“Many people have done this kind of component-level experiment, and now it’s time to integrate these parts into the embedded system;” Lee stressed: “I personally believe that if we can work together, this is achievable. ”

He also said that many researchers in Berkeley and other places are developing so-called "bio ASICs"; such components usually use fluid pulses in high/low voltage microfluidic channels, sometimes combined MEMS architecture. Bio-ASICs are the culmination of concepts in the field of electronics and natural science; for example, these components typically use three different layers of nano-masks to etch the engraved channels.

There is also a device designed to mimic the presence of cells in living tissue, creating a more dynamic environment for biological experiments than traditional Petri dishes. “We need to create a new platform for engineers to experiment with to control various conditions; therefore we need to create new culture dishes,” says Lee.

This type of bio ASIC is basically a lab-on-a-chip, which can be used to extract molecules in minutes or hours compared to traditional labs. The result of the level test.

Lee also introduced several methods for making nanoscale microscopes that can be used to extract spectral patterns of molecular elements in living cells. Some of the structures used in this type of device borrow from the eyes of insects in nature to create a dome-shaped array based on fluid pressure; others use a special charging structure that is inserted into the cell.

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