Model NO.: CAS: 83-88-5
Name: Vitamin B2
Molecular Weight: 376.37
Transport Package: 25kg/Drum, 25kg/Bag
HS Code: 2936230000
High Quality and Good Effect Riboflavin (vitamin B2) CAS 83-88-5
Vitamin B2-Riboflavin(Vitamin B2)USP/BP/EP;Flavaxin;Flavin BB;Flaxain;Food Yellow 15;Hyre;Lactobene;Lactoflavin;Lactoflavine;NCI 0033298;San Yellow B;Vitaflavine;Vitamin G;Vitamin B2;
Melting Point:290 Â°C (dec.)(lit.)
Solubility:Water solubility: 0.07 g/L (20 Â°C)
Appearance: Orange yellow crystalline powder
Package: 25kg/Drum, 25kg/Bag
Storage: Store in dry places and keep away from strong direct light and heat.
Application: Pharm, Food, Nutrition, Health Products
Riboflavin, also known asÂ vitamin B2, is aÂ vitaminÂ found in food and used as aÂ dietary supplement. As a supplement it is used to prevent and treatÂ riboflavin deficiencyÂ and preventÂ migraines. It may be given by mouth or injection.Â
It is nearly always well tolerated. Normal doses are safe duringÂ pregnancy. Riboflavin is in theÂ vitamin Bgroup. It is required by the body forÂ cellular respiration. Â Food sources includeÂ eggs,Â green vegetables, milk, and meat.
Riboflavin has been used in several clinical and therapeutic situations. For over 30 years, riboflavin supplements have been used as part of theÂ phototherapyÂ treatment ofÂ neonatal jaundice. The light used to irradiate the infants breaks down not onlyÂ bilirubin, the toxin causing the jaundice, but also the naturally occurring riboflavin within the infant's blood, so extra supplementation is necessary.
One clinical trial found that high-dose riboflavin appears to be useful alone or along with beta-blockers in the prevention ofÂ migraine. Â A dose of 400Â mg daily has been used effectively in the prophylaxis of migraines, especially in combination with a daily supplement ofÂ magnesium citrateÂ 500Â mg and, in some cases, a supplement ofÂ coenzyme Q10. Â However, two other clinical studies have failed to find any significant results for the effectiveness of B2 as a treatment for migraine.Â
Riboflavin in combination with UV light has been shown to be effective in reducing the ability of harmful pathogens found in blood products to cause disease. Â When UV light is applied to blood products containing riboflavin, the nucleic acids in pathogens are damaged, rendering them unable to replicate and cause disease. Â Riboflavin and UV light treatmentÂ has been shown to be effective for inactivating pathogens in platelets and plasma, and is under development for application to whole blood. Because platelets and red blood cells do not contain a nucleus (i.e. they have no DNA to be damaged) the technique is well-suited for destroying nucleic acid containing pathogens (including viruses, bacteria, parasites, and white blood cells) in blood products.Â
Corneal ectasia is a progressive thinning of the cornea; the most common form of this condition is keratoconus. Collagen cross-linking is a non-surgical treatment intended to slow progression of corneal ectasia by strengthening corneal tissue. The standard protocol calls for application directly to the eye of a 0.1% riboflavin solution for 30 minutes followed by 30 minutes of ultraviolet-A irradiation with a wavelength of 370Â nm and power of 3Â mW/cm2.
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