China Recommend Potent Anticonvulsant CAS 175481-36-4 Lacosamide

China Recommend Potent Anticonvulsant CAS 175481-36-4 Lacosamide


Product Name:LACOSAMIDE
Synonyms:LACOSAMIDE;(2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
CAS:175481-36-4
MF:C13H18N2O3
MW:250.29
Product Categories:Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;API;Pharmaceutical raw material;Other APIs;Inhibitors
Chemical Properties: White to Off-White Solid
Purity:99%
Package:1kg/25kg/package
Uses:A potent anticonvulsant.Lacosamide is an anticonvulsant and analgesic compound used for the treatment of partial-onset seizures and neuropathic pain. It can also used for the treatment of status epilepticus. Its analgesic effect is mediated by its inhibitory effect on sodium channels, which leads to neural membrane depolarization. Its interaction with the collapsin-response mediator protein 2 (CRMP-2 alias DRP-2) may also facilitate the above process, although the detailed mechanism remains to be elucidated. 


Lacosamide Description:

Lacosamide (LCM), (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037) is a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsant or antiepileptic drug. It reduces the spread of seizure activity in the brain. Lacosamide appears to have a dual mode of action: selective enhancement of sodium channel inactivation and modulation of collapsin response mediator protein-2.  Compared to novel antiepileptic drugs, lacosamide has broader and higher efficacy, better tolerability, and improved pharmacokinetic properties. Lacosamide is in phase III clinical development for adjunctive treatment of patients with uncontrolled partial-onset seizures, and for monotherapy of patients with painful diabetic neuropathy. It is absorbed rapidly and completely after oral administration. Lacosamide has an elimination half-life of approximately 13 hours and a low potential for drug interactions. Additionally, lacosamide exhibits linear, dose-proportional pharmacokinetics with low intra- and interpatient variability.





 
1, High quality with competitive price:
1)Standard: Enterprise Standard
2)All Purity≥99%
3)We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1)Parcel can be sent out in 24 hours after payment. Tracking number available
2)Secure and discreet shipment. Various transportation methods for your choice.
3)Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3, We have clients throughout the world.
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. China Recommend Potent Anticonvulsant CAS 175481-36-4 Lacosamide


Product Name:LACOSAMIDE
Synonyms:LACOSAMIDE;(2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
CAS:175481-36-4
MF:C13H18N2O3
MW:250.29
Product Categories:Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;API;Pharmaceutical raw material;Other APIs;Inhibitors
Chemical Properties: White to Off-White Solid
Purity:99%
Package:1kg/25kg/package
Uses:A potent anticonvulsant.Lacosamide is an anticonvulsant and analgesic compound used for the treatment of partial-onset seizures and neuropathic pain. It can also used for the treatment of status epilepticus. Its analgesic effect is mediated by its inhibitory effect on sodium channels, which leads to neural membrane depolarization. Its interaction with the collapsin-response mediator protein 2 (CRMP-2 alias DRP-2) may also facilitate the above process, although the detailed mechanism remains to be elucidated. 


Lacosamide Description:

Lacosamide (LCM), (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037) is a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsant or antiepileptic drug. It reduces the spread of seizure activity in the brain. Lacosamide appears to have a dual mode of action: selective enhancement of sodium channel inactivation and modulation of collapsin response mediator protein-2.  Compared to novel antiepileptic drugs, lacosamide has broader and higher efficacy, better tolerability, and improved pharmacokinetic properties. Lacosamide is in phase III clinical development for adjunctive treatment of patients with uncontrolled partial-onset seizures, and for monotherapy of patients with painful diabetic neuropathy. It is absorbed rapidly and completely after oral administration. Lacosamide has an elimination half-life of approximately 13 hours and a low potential for drug interactions. Additionally, lacosamide exhibits linear, dose-proportional pharmacokinetics with low intra- and interpatient variability.





 
1, High quality with competitive price:
1)Standard: Enterprise Standard
2)All Purity≥99%
3)We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1)Parcel can be sent out in 24 hours after payment. Tracking number available
2)Secure and discreet shipment. Various transportation methods for your choice.
3)Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3, We have clients throughout the world.
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

The grade A is 550 /50 grams. It requires uniform particle size, dry seeds, oil particles, impurities, moth eaten and mildew.
Lycium barbarum is rich in nutrients, but it is also a product that is difficult to preserve. Often due to environmental conditions, the emergence of insects, moldy, discoloration and so on. During storage, attention should be paid to controlling water content, temperature, oxygen content in the air, pest control and pest control. The fruit of Lycium barbarum takes longer time to bake and dry. It needs energy consumption or restricted by natural weather, and the processing cost is increased.

Skin aging is mainly caused by the oxidation of free radicals, and Lycium barbarum polysaccharides and B carotene are powerful antioxidants, together with the synergistic effect of trace elements selenium and vitamin E contained in Lycium barbarum, which constitute a powerful antioxidant force; in addition, vitrobiotic A can maintain the growth and differentiation of epithelial tissue. It can prevent skin dryness and keratosis of hair follicles, so as to beautifying and beautifying skin and moisturizing skin.

Red Goji Berry 550 Specifications

Red Goji Berry 550 Specifications,Dried Himalaya Goji,Black Himalaya Goji Berry,Quality Himalaya Goji Berry

Ningxia Hongqiaozhigu Technology&Development Co.,Ltd , http://www.guofuhui-ec.com