The role of Chinese medicine cell-level micro-grinding

Chinese herbal medicine, medicine, plant fiber superfine crushing machine
Overview:
MZ series Chinese medicine pulverizer uses the strong vibration of the vibration source to make the material in the pulverization chamber in the fluidized state, and is subjected to the high-strength collision, cutting, grinding and smashing force of the grinding rod.
The role of the material in a short time to achieve micron pulverization or cell wall breaking effect. At the same time, the pulverizer can also be used as a precision mixer and a cladding modifier. Tune
The intensity of the whole vibration can easily control the fineness of the material to be pulverized. Dry and wet pulverizing operations are also available. Designed and manufactured to meet GMP requirements, easy to assemble and disassemble, suitable for change
Material operation. It has various working configurations such as normal temperature, water cooling, low temperature, ultra-low temperature, anti-oxidation and anti-explosion, which can reduce the temperature in the pulverizing chamber and facilitate the powder of heat-sensitive materials.
broken. Widely used in Chinese herbal medicine, medicine, food, health products, cosmetics and other industries. It is a pulverizer with simple process and high cost performance.


Features:
â—†It is suitable for the crushing operation of toughness, fiber, sponge, high oil content and high sugar content which is difficult to be crushed by general pulverizer. It is also good for crushing hard and brittle materials.
â—† Suitable for plant pollen spores to break the wall and break the wall rate can reach 95%.
â—† Suitable for dry and wet crushing, precision mixing and coating modification.
â—†It is suitable for crushing operations with a medium diameter of up to micron.
â—†The equipment is easy to handle, clean and suitable for refueling operations.
â—†The pulverization process is fully sealed, no dust overflows, no environmental pollution.
◆The crushing chamber is equipped with a cooling water jacket, which can adjust the temperature and flow of water to control the temperature of the crushing chamber. A strong refrigeration system can also be configured to comminute the material at -30 ° C to 0 ° C.
â—†The pulverization process can be carried out in an inert atmosphere under riot and oxidation prevention.
â—†The design of the whole machine is reasonable, the amplitude is adjustable, and the working time is set, which is easy to operate.
â—†The equipment is easy to maintain and the running cost is extremely low.

The role of Chinese medicine cell-level micro-grinding

1. Improve bioavailability. In the pulverization operation, the cells of the traditional Chinese medicine can be broken in a certain amount, but the cell breaking rate of the coarse pulverizing operation is low, and the grinding particle diameter is larger than the cell diameter.
The lower the breaking rate. After the cells are broken, the contents of the broken cells can be directly contacted with the solvent, and the active ingredients can all directly enter the solvent and be absorbed by the human body. In the general pulverized particles and the pieces, most of the cells are intact, and the particles have several and dozens of particles. Even the root multi-cell composition. The dissolution of the active ingredient in the cell needs to pass through several or even dozens of cells to enter the solvent and then be absorbed by the body. And a considerable part of the cellular components can not enter the solvent through the cell wall, this part can only be thrown away. Therefore, the release amount and release rate of the active ingredient of the cell-level micropowder traditional Chinese medicine, the amount of the active ingredient absorbed by the human body per unit time will be higher than that of the traditional Chinese medicine powder obtained by the ordinary pulverization method.
The type of active ingredient of the drug released is also more than that of the ordinary smashing method. The onset time of the drug will be significantly shortened, and the effect of the drug on the human body will be more comprehensive and the intensity of action will be higher.

2. Homogenization in compound comminution. Most of the traditional Chinese medicine is a compound. The compound consists of various medicinal materials. After the cells are broken, the water and oil in the cells migrate out, so that the surface of the microparticles is semi-wet, and a stable particle cluster is formed between the particles and the particles (or Known as microparticles, each particle cluster contains the same proportion of traditional Chinese medicine ingredients. The physical structure of the particle cluster differs depending on the HLB value (hydrophilic, lipophilic balance), ductility, fragmentation, water (oil) rate, specific gravity, and the like, and different interactions of the components in the composition. This structure makes the active ingredients of the Chinese medicinal materials uniform, so that the various components are uniformly absorbed by the human body, which can also enhance the effect of the drug.

3. Improve the industrial extraction rate of active ingredients. Due to the high cell wall breaking rate, the dissolution resistance is reduced, and the cell-level micropowder is used in the Chinese medicine industry to extract the effective components of the drug, which will significantly increase the extraction rate. Some people have done the extraction test of saponins in Zhimu, and under the simplified industrial operating conditions, the extraction rate increased by 22.5%. The improvement of the extraction rate of macromolecular components is more obvious.

4. Reduce oral granules. Chocolate research shows that the average particle size of the material is about 25μm, and most of the particles have a particle size of 15-20μm. It tastes very good and has a good taste. When the average particle size exceeds 40μm, it can feel rough. The average particle size of the Chinese medicine compound cell-level pulverization operation is generally below 20μ.
20μ is fined to more than 75%, and its particle size is lower than the mouth particle sensation threshold, so there is no roughness when taken.

5. Additional effects. Since it is a cell-level smash, eggs that are comparable to the cell-scale scale will also be killed. Thereby reducing the threat of pests to Chinese herbal medicines.

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